Generic Sorbitrate (Isosorbide Dinitrate)

What is/are Isosorbide Dinitrate Tablets?

ISOSORBIDE DINITRATE is a type of vasodilator. It relaxes blood vessels, increasing the blood and oxygen supply to your heart. This medicine is used to prevent chest pain caused by angina. It will not help to stop an episode of chest pain. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care providers before I take this medicine?

They need to know if you have any of these conditions:

previous heart attack or heart failure an unusual or allergic reaction to isosorbide dinitrate, nitrates, other medicines, foods, dyes, or preservatives pregnant or trying to get pregnant breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. Take this medicine on an empty stomach, at least 30 minutes before or 2 hours after food. Do not take with food. Take your medicine at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly or your symptoms may get worse. Ask your doctor or health care professional how to gradually reduce the dose.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

Note: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following:

medicines used to treat erectile dysfunction (ED) like sildenafil, tadalafil, and vardenafil

This medicine may also interact with the following:

medicines for high blood pressure other medicines for angina or heart failure

This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What side effects may I notice from this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

bluish discoloration of lips, fingernails, or palms of hands irregular heartbeat, palpitations low blood pressure nausea, vomiting persistent headache unusually weak or tired

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

flushing of the face or neck rash

This list may not describe all possible side effects.

What should I watch for while using this medicine?

Check your heart rate and blood pressure regularly while you are taking this medicine. Ask your doctor or health care professional what your heart rate and blood pressure should be and when you should contact him or her. Tell your doctor or health care professional if you feel your medicine is no longer working.

You may get dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. To reduce the risk of dizzy or fainting spells, do not sit or stand up quickly, especially if you are an older patient. Alcohol can make you more dizzy, and increase flushing and rapid heartbeats. Avoid alcoholic drinks.

Do not treat yourself for coughs, colds, or pain while you are taking this medicine without asking your doctor or health care professional for advice. Some ingredients may increase your blood pressure.

Where should I keep this medicine?

Keep out of the reach of children.

Store at room temperature, approximately 25 degrees C (77 degrees F). Protect from light. Keep container tightly closed. Throw away any unused medicine after the expiration date.

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What is a generic medication?

Wikipedia gives the following definition:
“Generic drug (pl. generic drugs, short: generics) is a drug which is produced and distributed without a brand name. A generic must contain the same active ingredients as the original formulation. In most cases, it is considered bioequivalent to the brand name counterpart with respect to pharmacokinetic and pharmacodynamic properties. By extension, therefore, generics are assumed to be identical in dose, strength, route of administration, safety, efficacy, and intended use.”

Does a generic medication differ from a brand name drug?

Not much, actually. But there is a difference, of course. To see the difference more clearly we have made a table: click here

Comparison points	Comparison	Details
Active ingredient	same	Whether a manufacturer makes brand name drugs or generic drugs, the standards are the same. The ingredients are the most important element. The ingredient in the drug that helps cure you or make you feel better, is called the "medicinal" or active ingredient. While both generic and brand name drugs must have the same amounts of good quality medicinal ingredients, other ingredients are also found in drugs.
Effect	same	Since the active ingredient is the same, the effect produced by the generic drugs and the brand name drugs is the same.
Name	different	Generic medications cannot be manufactured under brand names since this is a copyright infringement case. Generics are usually named by their active ingredient names.
Shape	different	Shape of a pills is also a copyright of a brand, thus the shape of generic pills is different from the one of the original brand
Color	different	Color of a pills is also a copyright of a brand, thus the color of generic pills is different from the one of the original brand
Price	different	Generic medications are considerably cheaper than the brand name drugs.

Why are generic pills cheaper than the brand name ones?

The principal reason for the reduced price of generic medicines is that the creation of the generic drug runs up less cost and therefore a lower price can be offered and still maintain profitability.
Manufacturers of generic drugs are mainly able to avoid the following three costs that brand name pharmaceutical companies incur: (1) costs associated with the research and development of the drug; (2) costs associated obtaining regulatory approval (i.e. proving safety and efficacy of a drug); and (3) marketing costs.
First, Generic manufacturers do not incur the cost of drug discovery and instead reverse-engineer existing brand name drugs to allow them to manufacture bioequivalent versions.
Second, generic manufacturers do not bear the burden of proving the safety and efficacy of the drugs through clinical trials - rather, generic manufacturers must prove the generic drug’s bioequivalancy to the existing drug.
Third, these companies receive the large benefit of the marketing and advertising that goes into pushing the innovator drug. The brand name drug has to prove itself in the eyes of the consumer, generic ones do not. The drugs that generic manufacturers are selling have been on the market for usually a decade or more and do not need additional advertising. For the same reason, generic manufacturers also do not give away sample doses to promote their products. The significant research, development and marketing costs incurred by the large pharmaceutical companies in introducing a new drug to the market is often cited as the reason for the high cost of new agents - they wish to recover these costs before the patent expires. Generic manufacturers do not incur these costs, with bioequivalence testing and manufacturing costing relatively little, and are able to charge significantly less than the brand.

Where are the pills you offer shipped from?

The pills we offer are produced by Indian manufacturers. To make sure our entire product list is in stock, the orders are sent out directly by our manufacturer. Usually it takes approximately two weeks for an order to be delivered to your location but in some cases may take up to three weeks.

Are your pills FDA approved?

Since the medications we offer are produced in India they are approved by the Indian FDA. Our drug manufacturers perform a series of tests, both during and after production, to show that every drug meets the requirements for that product.